Exposure to toluene may occur from breathing ambient or indoor air affected by such sources. It is a good solvent (a substance that can dissolve other substances). The level of exposure depends upon the dose, duration, and work being done. Toluene. Toluene is an organic chemical compound having the chemical formula C 7 H 8 and is considered a hydrocarbon because it contains only carbon and hydrogen atoms. Toluene is typically used in a mixture with other solvents and chemicals such as paint pigments. 1.1. This means it's made up of carbon and hydrogen atoms, with a formula of C7H8. That's how it smells, too. Provides links and references to additional resources related to exposures to toluene. Toluene (), also known as toluol (), is an aromatic hydrocarbon. It is also added to gasoline to improve its octane rating. The central nervous system (CNS) is the primary target organ for toluene toxicity in both humans and animals for acute (short-term) and chronic (long-term) exposures. 4000, NIOSH Immediately Dangerous to Life or Health Concentrations (IDLH): Toluene, NIOSH Worker Notification Program: Shoe Manufacturers, Agency for Toxic Substances and Disease Registry (ATSDR): ToxFAQs™ for Toluene, ATSDR’s Medical Management Guidelines: Toluene, EPA Acute Exposure Guideline Levels: Toluene, EPA Consumer Fact Sheet Ground and Drinking Water: Toluene, EPA Integrated Risk Information System: Toluene, NLM Hazardous Substance Data Bank: Toluene, NLM (Household Products Database): Toluene, Canadian Centre for Occupational Health and Safety: Toluene, OECD Global Portal to Information on Chemical Substances: Toluene, WHO (Environmental Health Criteria 52): Toluene, National Institute for Occupational Safety and Health, U.S. Department of Health & Human Services, Workers in locations where there are leaking underground gasoline storage tanks, Construction workers who use paint, adhesives or solvents, Workers involved with the production of gasoline. It is produced in the process of making gasoline and other fuels from crude oil and in making coke from coal. 2549), NIOSH PUB: Toluene Diffusive sampler, No. This page links to additional information about: Provides information on training workers who use materials containing toluene about the health and safety hazards of toluene, how to recognize exposure to toluene, and the protective measures that apply to the use of toluene in the specific work area. Toluene, also known as methylbenzene, is a clear, colorless liquid with a distinctive sweet smell that is widely used in industrial settings as a solvent. The odor of toluene is sweet, pungent, benzene-like and gives a smell of paint thinner. It is a mono-substituted benzene derivate. Toluene is a colourless liquid and water-insoluble liquid. This structural difference has led to various differences in their reactivity and usage. Toluene vapor has a sharp or sweet odor, which is a sign of exposure. Toluene is added to gasoline, used to produce benzene, and used as a solvent. Product form : Substance Substance name : Toluene CAS-No. Its other name is methylbenzene, and chemists illustrate it by drawing a six-sided benzene ring and adding a methyl group to it. In short, it's a type of paint thinner, or, if you want to get technical, an industrial solvent. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. What is the WHMIS 1988 classification? Toluene can remain unchanged for a long time in soil or water that is not in contact with air. FOUND IN: Nail polish, nail treatment, hair dyes Exposure to toluene can cause eye and nose irritation, tiredness, confusion, euphoria, dizziness, headache, dilated pupils, tears, anxiety, muscle fatigue, insomnia, nerve damage, inflammation of the skin, and liver and kidney damage. Toluene exposures have been studied in nail salons and printing establishments, auto repair, and construction activities. Toluene: Toluene is an organic compound having a benzene ring attached to a methyl group. What is the WHMIS 1988 classification? Workers can be exposed to toluene by breathing it in, getting it on their skin, getting it splashed into their eyes, or swallowing it. Toluene definition is - a liquid aromatic hydrocarbon C7H8 that resembles benzene but is less volatile, flammable, and toxic and is used especially as a solvent, in … A volatile petrochemical solvent and paint thinner, toluene is a potent neurotoxicant that acts as an irritant, impairs breathing, and causes nausea. Products that may contain toluene-such as paint, metal cleaners and adhesives-are used in many industries and can be found in many workplaces. Colorless and insoluble in water, toluene can be dangerous when its fumes are inhaled, causing neurological damage and intoxication. Transportation . It is considered an aromatic solvent because it possesses a benzene ring in which six carbon atoms connect with each other from alternating double bonds that create a hexagonal ring called a benzene ring. Toluene is a solvent used to make some paint thinners, adhesives, and nail care products. Search the HHE database for more information on chemical topics. As a solvent, toluene can be used in paints, paint thinners, adhesives, inks, resins, cleaning agents, leather tanners and inks. The oral LD(50) for toluene in rats is 7.53 ml/kg (Smyth, Carpenter, Weil et al. Toluene is an aromatic hydrocarbon solvent and natural sources of toluene include crude oil and small quantities it is found in tolu tree.Toluene alternative names include methylbenzene, toluol, anisen, phenyl methane. What are other names or identifying information for toluene? Sigma-Aldrich offers a number of Toluene products. Many of the products we rely upon every day are safer and more comfortable through the use of polyurethanes made possible by diisocyanates. Toluene (C₆H₅CH₃) is a colorless liquid with a sweet, pungent odor. What is Toluene used for? Without proper ventilation and safety precautions, toluene can cause irritated eyes, nose, and throat; dry or cracked skin; headache, dizziness, feeling of being drunk, confusion and anxiety. Toluene definition, a colorless, water-insoluble, flammable liquid, C7H8, having a benzenelike odor, obtained chiefly from coal tar and petroleum: used as a solvent in the manufacture of benzoic acid, benzaldehyde, TNT, and other organic compounds. As such, its IUPAC systematic name is methylbenzene. Toluene definition is - a liquid aromatic hydrocarbon C7H8 that resembles benzene but is less volatile, flammable, and toxic and is used especially as a solvent, in … Toluene occurs naturally in crude oil and in the tolu tree. Toluene-D8 | C7H8 | CID 74861 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. The key difference between toluene and xylene is that toluene contains one methyl group attached to a benzene ring whereas xylene contains two methyl groups attached to a benzene ring.. Toluene Restriction list, Substance Evaluation - CoRAP, Pre-Registration process, Other, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, Ambient Air Quality Directive, Annex X - Ozone Precursor Substances, Occupational Exposure Limits - 2nd list - Indicative OELVs , EU. Toluene (methyl benzene) is a chemical that is widely used in various substances within the home such as glue, paint and paint removers, and polish. It comprises 15–20 percent of coal-tar light oil and is a minor constituent of petroleum. Toluene is a toxic chemical used in in nail products and hair dyes. Toluene toxicity refers to the harmful effects caused by toluene on the body. The application of TLV's is discussed in the Statement of Position Regarding the TLVs and BEIs. Incompatible with strong oxidizing agents. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. What are other names or identifying information for toluene? Potentially violent polymerization reaction with strong bases or acyl chlorides. Toluene is a flammable, colorless liquid with an aromatic hydrocarbon odor. Both sources provide toluene for commercial use, but larger amounts are made by catalytic r ; 2,6-Diaminotoluene, a common impurity in 2,4-diaminotoluene; 2,5-Diaminotoluene, precursor to hair dyes. Current OSHA PEL: 200 ppm TWA, 300 ppm CEILING, 1989 OSHA PEL: 100 ppm (375 mg/m 3) TWA, 150 ppm (560 mg/m 3) STEL. von Sirel. Biological use: Toluene can also be used for biological purposes. Toluene 108-88-3 Hazard Summary Toluene is added to gasoline, used to produce benzene, and used as a solvent. Toluene is a clear, colorless liquid which becomes a vapor when exposed to air at room temperature. ; Proposition 65 requires businesses to determine if they must provide a … It is an aromatic hydrocarbon that is widely used as an industrial feedstock and as a solvent. Found in nature in a type of balsam tree called the tolu balsam, as well as in crude oil; toluene is also present in the environment as a result of its use as an additive in such products as nail polish, cigarettes, gasoline, dyes, perfume, explosives, paints and thinners, adhesives, and other manufactured goods. Toluene is an aromatic hydrocarbon. Recreational use: Toluene, in the manner of recreational use, is used as an intoxicative inhalant. Toluene is a clear, colorless liquid with a distinctive smell. These types of exposures may make workers sick immediately or cause effects over time. It's a colorless liquid with a sweet smell and taste. Toluene is also found in car exhaust and the smoke from cigarettes. Toluene. Its IUPAC systematic name is methylbenzene. The acute toxicity of toluene in animals is greater than that of benzene. Learn more about exposure limits here. The TLV for toluene was established to protect against subclinical changes in color vision and the potential for spontaneous abortion in female workers. Work. A bulk solvent exporter would normally distribute this solvent in bulk vessels or tank trucks. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 03/21/2014 Revision date: … It is smell like paint thinners. Gasoline and other fuels also contain toluene. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Toluene is the main chemical that causes many of the signs and symptoms seen with inhalation of glue and paint. To a 250 ml conical flask, N-acetylglycine (0.177 g, 1 mmol) was suspended in toluene (5.3 ml), heated the solution and stirred until it was clear and then a solution of isocyanate or diisocyanate (0.16 ml, 1 mmol) in chloroform (5.7 ml) was added drop wise and refluxed for 2 hrs after addition of 3-4 drops of triethylamine and then cooled to room temperature (25 AdegC). See more. Exposure to toluene can result in temporary effects such as headaches, dizziness and cracked skin, as well as more serious effects such as reproductive damage and respiratory complications. It is a mono-substituted benzene derivative, consisting of a methyl group (CH₃) attached to a phenyl group. Saving Lives, Protecting People, New Jersey Hazardous Substance Fact Sheets: Toluene, The National Institute for Occupational Safety and Health (NIOSH), Managing Chemical Safety in the Workplace, NMAN: S-Benzylmercapturic acid and S-phenylmercapturic acid in urine 8326, NIOSH Criteria for a Recommended Standard: Occupational Exposure to Toluene, NIOSH Occupational Health Guideline for Toluene, NIOSH Volatile Organic CPDS (Screening) (No. Toluene should be kept out of direct sunlight, heat and open flames. Toluene is on the Proposition 65 list because it can cause birth defects or other reproductive harm.Significant exposure to toluene during pregnancy may affect the baby’s development. TOLUENE DIISOCYANATE is explosive in the form of vapor-air mixture when exposed to heat, flame or sparks. It has the strong and sweet smell of paint thinner, but this isn't what makes it aromatic. Explosions have been reported [NFPA 491M 1991]. Reaction with aniline may generate enough heat to ignite unreacted portion and surrounding materials. Toluene: Toluene has a sweet, pungent odor. Toluene is a clear, colorless liquid which becomes a vapor when exposed to air at room temperature. Workers may be harmed from exposure to toluene. Its chemical formula is C 7 H 8.Toluene is a commonly used solvent and diluent in paint, paint thinner, and certain glues, where it is responsible for those substances' characteristic odors. Patty (1963b, as cited in ACGIH 1986/Ex. Identification . Toluene Safety Data Sheet according to Federal Register / Vol. It has also been used in the formulation of nail products to enable nail polishes, hardeners and lacquers to be applied smoothly. Because of this, toluene is sometimes abused as an inhalant drug. That use of Toluene was first pioneered by the Honda team. Toluene is an aromatic hydrocarbon consisting of a CH 3 group attached to a phenyl ring. Toluene disrupts normal functioning of the cardiovascular and gastrointestinal system by destabilizing the heart’s electrical activity, irritating the stomach and intestinal lining and potentially causing liver failure. Exposure to toluene can cause eye and nose irritation, tiredness, confusion, euphoria, dizziness, headache, dilated pupils, tears, anxiety, muscle fatigue, insomnia, nerve damage, … Provides the occupational exposure limits for toluene. Toluene, aromatic hydrocarbon used extensively as starting material for the manufacture of industrial chemicals. The Health Hazard Evaluation Program (HHE) conducts onsite investigations of possible worker exposure to chemicals. It is also widely used for various industrial purposes. Toluene is produced during the process of making gasoline and other fuels from crude oil, in making coke from coal, and as a by-product in the manufacture of styrene. Toluenediamine may refer to these isomeric organic compounds with the formula C 6 H 3 (NH 2) 2 (CH 3): . But how is toluene made? Unintentional chronic exposure to toluene is mainly seen among workers handling substances that contain the chemical. Wikipedia It’s used in paints, dyes, solvents, fingernail polish, and gasoline. The following resources provide information about occupational exposure to toluene. It has the smell that is often associated with paint thinners. Before this question can be answered you must explain why you need the answer. Reaction with water liberates carbon dioxide. Toluene (C₆H₅CH₃) is a colorless liquid with a sweet, pungent odor. It is produced in the process of making gasoline and other fuels from crude oil and in … TOLUENE reacts vigorously with allyl chloride or other alkyl halides even at -70° C in the presence of ethyl aluminum dichloride or ethyl aluminum sesquichloride. An answer is that toluene is benzene with a methyl group stuck on it. 2,4-Diaminotoluene, precursor to toluene diisocyanate and azo dye. Toluene is volatile meaning that it disperses into the air and can thereby be inhaled. Toluol, Trivialname nach IUPAC auch Toluen, Methylbenzol, Phenylmethan, nach IUPAC-Nomenklatur Methylbenzen genannt, ist eine farblose, charakteristisch riechende, flüchtige Flüssigkeit, die in vielen ihrer Eigenschaften dem Benzol ähnelt. The key difference between benzene and toluene is their structure; toluene has a methyl group attached to the benzene ring while benzene has no methyl groups attached.. Benzene and Toluene are two aromatic compounds having a slight difference between them in their structure. Toluene, or also known as toluol, is an aromatic hydrocarbon. Odor. It is categorized as such because of the presence of carbon (C) atoms in its chemical formula, C7H8. Toluene at 86% fueled all turbocharged engines in Formula one during the 1980s. Toluene, also known as methylbenzene, is an organic chemical compound. Insoluble in water, it is a colorless liquid with an odor similar to that of paint thinners. Toluene is also flammable, and its vapors can be ignited by flames, sparks or other ignition sources. Exposure to toluene can result in temporary effects such as headaches, dizziness and cracked skin, as well as more serious effects such as reproductive damage and respiratory complications. Benzene: The molar mass of benzene is about 78.11 g/mol. Workers using toluene-containing paints, varnishes, shellac, nail polish, glues and adhesives, rust preventives or printing inks may be exposed to toluene. Hence it was named toluene. Toluene is used in many industries. Toluene is an aromatic solvent that is primarily used as a thinner or diluent in several end-user products, such as paints, coatings and cleaners. Benzene: Benzene is an aromatic compound having the chemical formula C 6 H 6. 77, No. Toluene exposure can be unintentional or intentional. The central nervous system (CNS) is the primary target organ for toluene toxicity in both humans and animals for acute (short-term) and chronic (long-term) exposures. Toluene, aromatic hydrocarbon used extensively as starting material for the manufacture of industrial chemicals. Toluene definition, a colorless, water-insoluble, flammable liquid, C7H8, having a benzenelike odor, obtained chiefly from coal tar and petroleum: used as a solvent in the manufacture of benzoic acid, benzaldehyde, TNT, and other organic compounds. Toluol ist ein aromatischer Kohlenwasserstoff, häufig ersetzt es als Lösungsmittel das giftige Benzol. See more. An answer is that toluene is benzene with a methyl group stuck on it. Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. What products containing TDI and related compounds are available to consumers? It comprises 15–20 percent of coal-tar light oil and is a minor constituent of petroleum. Kindle 9,95 € 9,95 € Sofort lieferbar. How does exposure to toluene occur? You will be subject to the destination website's privacy policy when you follow the link. Toluene: The molar mass of toluene is about 92.14 g/mol. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 03/21/2014 Revision date: 02/27/2018 Supersedes: 03/21/2014 Version: 1.1 02/27/2018 EN (English) Page 1 SECTION 1: Identification . Products with this Ingredient Toluene (C₆H₅CH₃) is a colorless liquid with a sweet, pungent odor. Exposure to toluene can cause eye and nose irritation, tiredness, confusion, euphoria, dizziness, headache, dilated pupils, tears, anxiety, muscle fatigue, insomnia, nerve damage, inflammation of the skin, and liver and kidney damage Its chemical formula is C 7 H 8.Toluene is a commonly used solvent and diluent in paint, paint thinner, and certain glues, where it is responsible for those substances' characteristic odors. Toluene was first derived from reagent named Tolu Balsam. If you work in an industry that uses toluene, please read chemical labels and the accompanying Safety Data Sheets for hazard information. What are the most important things to know about toluene in an emergency? Toluene is typically used in a mixture with other solvents and chemicals such as paint pigments. Both these are aromatic compounds containing benzene rings and attached methyl group(s). Toluene is produced during the process of making gasoline and other fuels from crude oil, in making coke from coal, and as a by-product in the manufacture of styrene. Consumers could be exposed to these chemicals while using products containing uncured or unhardened TDI and its related compounds. It is colorless and insoluble in water. It can also be referred as methylbenzene, anisen, and phenyl methane. Toluene is an aromatic hydrocarbon. Toluene. Toluene is an aromatic hydrocarbon consisting of a CH 3 group attached to a phenyl ring. Toluene diisocyanate unspecified isomers (Benzene, 1,3-diisocyanatomethyl-, CASRN 26471-62-5) Q5. OSHA's exposure limits for toluene have been set to prevent effects of long term exposure on the nervous system, however, workers frequently experience symptoms of toluene exposure in activities where exposures are lower than OSHA's present exposure limits. , can cause liver and kidney damage some paint thinners C 6 H 5 CH.. 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